# Shilajit research library: every human trial

Source: https://shilajit.uk/research/
Author: Sam Rowan · Updated 2026-10-16

**Short answer:** About a dozen human studies have tested shilajit on its own, most with fewer than 100 people and lasting 8 to 12 weeks. The strongest are randomised, placebo-controlled trials on testosterone, bone density, fracture healing and muscle strength. None has been independently repeated, and many tested one branded extract.

## Which human trials have tested shilajit?

These are the published human studies that gave shilajit on its own and measured a health outcome, newest first. "RCT" means a randomised controlled trial with a placebo group, the most reliable design.

| Study | Design | People | Dose and length | Main finding |
| --- | --- | --- | --- | --- |
| Yadav 2026 | Open-label, no placebo | 25 healthy men, 21 to 55 | 500 mg resin a day, 28 days | Strength, endurance and fatigue scores improved from baseline |
| Neltner 2024 | RCT | 35 trained young men | 500 or 1,000 mg a day, 8 weeks | Blood marker of collagen production rose |
| Pingali 2022 | RCT, double-blind | 60 postmenopausal women with osteopenia | 250 or 500 mg a day, 48 weeks | Bone loss in spine and hip slowed, more at 500 mg |
| Sadeghi 2020 | RCT, double-blind | 160 adults with a broken shin bone | 1,000 mg a day, 28 days | Bone healed in 129 days vs 153 on placebo |
| Das 2019 | Placebo-controlled, assessor-blinded | 45 healthy women aged 30 to 65 | 250 or 500 mg a day, 14 weeks | Skin blood flow improved at 500 mg |
| Keller 2019 | RCT | 63 active young men | 250 or 500 mg a day, 8 weeks | Less strength loss during fatigue at 500 mg, in the stronger half only |
| Pandit 2016 | RCT, double-blind | Healthy men aged 45 to 55 | 500 mg a day, 90 days | Total and free testosterone and DHEA-S rose vs placebo |
| Das 2016 | Single group, no placebo | 16 overweight adults (29 enrolled) | 500 mg a day, 12 weeks | Genes linked to muscle repair switched on; no safety issues |
| Biswas 2010 | Single group, no placebo | 28 men with low sperm counts | 200 mg a day, 90 days | Sperm count up 61%, testosterone up 24% from baseline |
| Sharma 2003 | Placebo-controlled; groups not compared statistically | 30 medical students (20 shilajit, 10 placebo) | 2 g a day, 45 days | Lower cholesterol and triglycerides, higher HDL |

A further 2025 trial in 166 adults at risk of metabolic syndrome tested a supplement containing chromium, amla (*Phyllanthus emblica*) and a very small amount of shilajit (6 or 12 mg a day) alongside diet and exercise (Martinez et al., 2025). Because shilajit was a minor ingredient in a combination, it tells us little about shilajit itself. The same applies to a 2021 trial of BrainUp-10, a shilajit and B-vitamin product, in 82 people with Alzheimer's disease (Guzman-Martinez et al., 2021).

## What are the main limitations of shilajit research?

- **Small trials.** Most included fewer than 100 people, and several fewer than 40. Small trials can miss real effects and exaggerate chance ones.
- **No independent replication.** No result has been confirmed by a second, independent team.
- **One product dominates.** Many trials used PrimaVie, a purified extract from the company Natreon, which also funded several of them, and four of the six authors of the 2026 resin study work for a supplement company. Findings may not apply to other products, particularly raw resin.
- **Surrogate outcomes.** Several studies measured blood markers or gene activity rather than things people notice, such as strength, energy or fewer fractures.
- **Mostly men.** Only two of these studies focused on women, and none included children or focused on people over 65.

## What do the reviews conclude?

A 2014 review concluded that shilajit appears safe and shows promise for fatigue, physical performance and male fertility, but that "additional well-controlled human and animal studies involving the use of standardized products are needed" (Stohs, 2014). A 2024 systematic review of testosterone boosters rated purified shilajit extract as "possibly effective" for men with age-related low testosterone, one of only a few supplements to get that rating (Morgado et al., 2024).

## Where does this research fit on the site?

Each finding feeds the evidence grades on [shilajit benefits](/benefits/), the doses in our [shilajit dosage guide](/how-to-take-shilajit/dosage/) and the safety data in [is shilajit safe?](/safety/). We add new trials to this library as they are published. If we've missed one, please [tell us](/contact/).

## Frequently asked questions

### How many clinical trials have been done on shilajit?

We count 10 published human studies of shilajit on its own, 7 of them with a placebo group. Most of the 160 or so papers on shilajit in PubMed are animal, lab or chemistry studies, or reviews.

### Who funds shilajit research?

Several trials tested PrimaVie, a branded extract made by Natreon, and at least one study was run by a shilajit manufacturer. Industry funding doesn't make results wrong, but independent replication would make them more convincing.

## References

1. [PubMed search: shilajit OR mumijo OR mumie](https://pubmed.ncbi.nlm.nih.gov/?term=shilajit+OR+mumijo+OR+mumie) 161 results when checked on 16 October 2026.
2. [Pandit S et al. Clinical evaluation of purified Shilajit on testosterone levels in healthy volunteers. Andrologia. 2016;48(5):570-5.](https://pubmed.ncbi.nlm.nih.gov/26395129/)
3. [Biswas TK et al. Clinical evaluation of spermatogenic activity of processed Shilajit in oligospermia. Andrologia. 2010;42(1):48-56.](https://pubmed.ncbi.nlm.nih.gov/20078516/)
4. [Keller JL et al. The effects of Shilajit supplementation on fatigue-induced decreases in muscular strength and serum hydroxyproline levels. J Int Soc Sports Nutr. 2019;16(1):3.](https://pubmed.ncbi.nlm.nih.gov/30728074/)
5. [Neltner TJ et al. Effects of 8 Weeks of Shilajit Supplementation on Serum Pro-c1α1, a Biomarker of Type 1 Collagen Synthesis. J Diet Suppl. 2024;21(1):1-12.](https://pubmed.ncbi.nlm.nih.gov/36546868/)
6. [Pingali U, Nutalapati C. Shilajit extract reduces oxidative stress, inflammation, and bone loss to dose-dependently preserve bone mineral density in postmenopausal women with osteopenia. Phytomedicine. 2022;105:154334.](https://pubmed.ncbi.nlm.nih.gov/35933897/)
7. [Sadeghi SMH et al. Efficacy of Momiai in Tibia Fracture Repair: A Randomized Double-Blinded Placebo-Controlled Clinical Trial. J Altern Complement Med. 2020;26(6):521-528.](https://pubmed.ncbi.nlm.nih.gov/32310691/)
8. [Das A et al. The Human Skeletal Muscle Transcriptome in Response to Oral Shilajit Supplementation. J Med Food. 2016;19(7):701-9.](https://pubmed.ncbi.nlm.nih.gov/27414521/)
9. [Das A et al. Skin Transcriptome of Middle-Aged Women Supplemented With Natural Herbo-mineral Shilajit. J Am Coll Nutr. 2019;38(6):526-536.](https://pubmed.ncbi.nlm.nih.gov/31161927/)
10. [Sharma P et al. Shilajit: evaluation of its effects on blood chemistry of normal human subjects. Anc Sci Life. 2003;23(2):114-9.](https://pubmed.ncbi.nlm.nih.gov/22557121/)
11. [Yadav D et al. Safety and Efficacy of TruBlk Shilajit Resin Supplementation on Physical Performance and Blood Biomarkers in Healthy Adults: A 28-Day Open-Label Pilot Study. Cureus. 2026;18(1):e102372.](https://pubmed.ncbi.nlm.nih.gov/41613504/)
12. [Martinez V et al. Effects of 12 Weeks of Chromium, Phyllanthus emblica Fruit Extract, and Shilajit Supplementation on Markers of Cardiometabolic Health. Nutrients. 2025;17(12):2042.](https://pubmed.ncbi.nlm.nih.gov/40573153/)
13. [Guzman-Martinez L et al. Interventional Study to Evaluate the Clinical Effects and Safety of the Nutraceutical Compound BrainUp-10 in a Cohort of Patients with Alzheimer's Disease. J Alzheimers Dis. 2021;81(3):1231-1241.](https://pubmed.ncbi.nlm.nih.gov/33935080/)
14. [Morgado A et al. Do 'testosterone boosters' really increase serum total testosterone? A systematic review. Int J Impot Res. 2024;36(4):348-364.](https://pubmed.ncbi.nlm.nih.gov/37697053/)
15. [Stohs SJ. Safety and efficacy of shilajit (mumie, moomiyo). Phytother Res. 2014;28(4):475-9.](https://pubmed.ncbi.nlm.nih.gov/23733436/)
